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Table 3 Square roots of MSE values (in cM) for both methods for two haplotype lengths: the QTL and its two flanking markers and the QTL and its four flanking markers

From: Does probabilistic modelling of linkage disequilibrium evolution improve the accuracy of QTL location in animal pedigree?

Param

 

Methods

  

HaploMax

HAPimLDL

Number of markers

 

2

4

2

4

N s

20

1.66

1.26

1.66

1.26

N p

100

    

N s

100

1.65

1.11

1.71

1.15

N p

20

    

N s

20

1.68

1.36

1.74

1.45

N p

50

    

N s

50

1.73

1.32

1.83

1.46

N p

20

    

N s

20

1.73

1.39

1.81

1.47

N p

25

    

N s

25

1.83

1.49

1.85

1.59

N p

20

    

N s

50

1.82

1.57

1.98

1.53

N p

10

    

N s

10

1.85

1.41

1.92

1.61

N p

50

    
  1. Square roots of MSE values (in cM) for both methods for two haplotype lengths: the QTL and its two flanking markers and the QTL and its four flanking markers; we assumed complete linkage disequilibrium between the QTL and the markers and linkage equilibrium between the markers in the founder population; the true QTL position is 3.35 cM on a 10-cM long chromosomal region; the QTL allelic effect value is equal to 1, the effective size of the population is equal to 100, the number of generations is equal to 50 and the marker density is equal to 0.5 cM; N s is the number of sires and N p is the number of progeny per sire; each scenario was simulated 500 times