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Table 1 Average and maximum absolute differences for type 1 error rate and power between simulated* and theoretical results

From: Statistical distributions of test statistics used for quantitative trait association mapping in structured populations

 

Model

 

Regression

GRAMMAR

FASTA

QTDT

Type 1 error (%)

    

Average difference

0.26

0.22

0.18

0.28

Maximum difference

1.09

0.70

0.50

0.74

Power (%)

    

Average difference

0.37

0.58

0.90

1.12

Maximum difference

0.76

2.97

1.74

2.19

  1. *see text: total population size = 600 with 120, 20 and 10 sires that respectively produced 5, 30 and 60 offspring, MAF of SNP 0.5, QTL effect 2% of phenotypic variance, assumed type 1 error rate 5%, heritability from 0 to 1 in steps of 0.1.
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Genetics Selection Evolution

ISSN: 1297-9686