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Table 1 Characterisation of QTL influencing parasite resistance traits that exceed the 5% chromosome-wise significance threshold in the commercial population of Spanish Churra sheep analysed in this study

From: Quantitative trait loci for resistance to trichostrongylid infection in Spanish Churra sheep

ACROSS-FAMILY ANALYSIS WITHIIN-FAMILY ANALYSIS
Chr.1 Trait
Position2
[95% CI]3
Flanking interval4 Pc5 ( P g )6 Segregating families
Pc7
Position8 Flanking interval9 Size effect10 (SD units)
1 IgA
35 cM
[1-320].
BMS835-ILSTS044 0.038 Family 1
0.005
38 cM
BMS835-ILSTS044
0.111
(1.70 SD)
  LFEC 1
152 cM
[122-374]
INRA006-BMS574 0.016 Family 8
0.013
134 cM
INRA006-BMS574
0.129
(1.31 SD)
6 LFEC 1
84 cM
[49-140]
BM4621-CSN3 0.002
(0.041)
Family 1
0.002
Family 2
0.041
Family 7
0.049
79 cM
BM4621-CSN3
113 cM
CSRD2158-MCM214
105 cM
CSN3-CSRD2158
0.160
(1.63 SD)
0.082
(0.83 SD)
0.117
(1.19 SD)
10 LFEC 0
59-60 cM
[1-95]
BM4621-CSN3 0.018 Family 7
0.014
65 cM
BMS975-TGLA441
0.324
(2.53 SD)
14 LFEC 0
1-2 cM
[1-125]
TGLA357-CSRD247 0.018 Family 1
0.029
Family 6
0.015
2 cM
TGLA357-CSRD247
1-2 cM
TGLA357-CSRD247
0.137
(1.07 SD)
0.136
(1.06 SD)
  1. 1 Chromosome number
  2. 2,8 Position (cM Haldane) of the chromosome where the maximum F-statistic value was obtained in the across- and within-family analyses, respectively
  3. 3 The 95% confidence interval obtained by bootstrapping analysis [26] is shown in square brackets (cM Haldane)
  4. 4,9 Markers flanking the position of the maximum F-statistic in the across-family and within- analysis, respectively. Markers in bold caps are < 1 cM from the maximum F-statistic
  5. 5,7 Pc = chromosome-wide p-value obtained by permutation test for that position [23]
  6. 6 P g = genome-wide p-value for that position obtained by applying the following Bonferroni correction: P genomewide = 1-(1-P chromosomewise )(1/r), where r indicates the contribution of the chromosome to the total genome length [24]; only indicated for P g < 0.05
  7. 10 Magnitude of the allelic substitution effect calculated for each segregating family, expressed in units of the trait (egg count/g faeces for LFEC0 and LFEC1, D.O ratio for IgA and mUTyr Peps) and in phenotypic SD units of the analysed YDs (value in brackets)