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Table 4 Direct heritability (h2) estimates for total and differential WBC and PBML subsets for SPF and non-SPF pigs1, 2,

From: Traits associated with innate and adaptive immunity in pigs: heritability and associations with performance under different health status conditions

Farm SPF     Non-SPF    
Trait Direct h2 (s.e.) Pen effect (s.e.) Genetic variance × 10-1 Residual variance × 10-1 Direct h2 (s.e.) Pen effect (s.e.) Genetic variance × 10-1 Residual variance × 10-1
WBC 0.29 (0.13) NS 0.32 0.72 0.28 (0.11) NS 0.21 0.55
MNL% 0.09 (0.10) 0.16 (0.06)* 0.03 2.02 0.29 (0.13) NS 0.96 2.10
PMNL% 0.09 (0.10) 0.17 (0.06)* 0.56 4.60 0.36 (0.14) NS 3.00 5.20
PBML subsets:         
CD4+ 0.78 (0.12) NS 187 38.3 0.57 (0.14) 0.06 (0.04)* 147 94.1
CD8α+ 0.35 (0.12) NS 168 306 0.60 (0.16) 0.12 (0.05)* 215 141
CD4+CD8α+ 0.34 (0.15) NS 0.58 1.10 0.37 (0.17) NS 0.46 0.79
CD4+CD8α- 0.82 (0.17) NS 0.95 0.19 0.45 (0.21) NS 0.35 0.43
CD8αβ+ 0.48 (0.16) NS 0.42 0.45 0.36 (0.17) NS 0.32 0.56
CD11R1+ total 0.46 (0.12) NS 0.45 0.52 0.07 (0.08) 0.34 (0.08)* 0.09 0.78
CD11R1+CD8α+ 0.46 (0.13) NS 0.11 0.13 0.31 (0.16) NS 0.73 1.60
CD11R1+CD8α- 0.27 (0.11) 0.13 (0.06)* 0.39 0.88 0.27 (0.14) NS 0.30 0.70
γδ+ T cells 0.46 (0.12) 0.05 (0.04) 233 279 0.30 (0.12) NS 141 317
B cells 0.41 (0.12) NS 0.55 0.80 0.14 (0.11) NS 0.15 0.86
monocytes 0.26 (0.11) 0.11 (0.05)* 0.42 1.00 0.26 (0.13) NS 0.32 0.91
CD14 + 0.04 (0.09) NS 0.08 1.90 0.48 (0.18) NS 1.00 1.10
CD16+ 0.25 (0.13) NS 0.16 0.47 0.05 (0.09) 0.09 (0.05)* 0.04 0.83
  1. 1Traits for which the heritability differed significantly between SPF and non-SPF farms are shown in bold (* p < 0.05). 2 White blood cells expressed as no. cells × 106/mL, PBML sub-sets expressed as proportion of mononuclear leucocytes and antigen density expressed as the number of antibody binding sites per cell (see Materials and Methods).