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Table 5 - Liver mRNA expressions § in 6-week old and 12-week old SUS and RES quail fed the regular diet

From: Differential mRNA expression of seven genes involved in cholesterol metabolism and transport in the liver of atherosclerosis-susceptible and -resistant Japanese quail strains

Gene Effect 6-week old 12-week old
RES (N = 7) SUS (N = 6) RES (N = 6) SUS (N = 6)
HMGCR *P < 0.02 1.110 ± 0.110 0.688 ± 0.110 1.009 ± 0.110 0.864 ± 0.110
FDFT1 *P < 0.01 1.359 ± 0.217 0.558 ± 0.217 1.082 ± 0.217 0.638 ± 0.217
DHCR7 †P < 0.01 1.423 ± 0.250 1.359 ± 0.250 0.995 ± 0.250 0.829 ± 0.250
SQLE *P < 0.02 2.430 ± 0.483 0.414 ± 0.522 1.026 ± 0.522 0.370 ± 0.522
ABCG5 *†P < 0.0005 0.594 ± 0.076b 0.547 ± 0.082b 1.288 ± 0.082a 0.586 ± 0.082b
ABCG8 *P < 0.01; † P < 0.01 0.724 ± 0.189 0.531 ± 0.204 1.654 ± 0.204 0.687 ± 0.204
APAO1 †P < 0.0001 0.626 ± 0.093 0.448 ± 0.101 1.126 ± 0.101 1.123 ± 0.101
  1. N = number of individuals measured; total number of individuals = 25; *denotes significant strain effect; †denotes significant age effect; *†denotes significant strain x age interaction; §all values (± SEM) indicate the gene of interest relative to GAPDH (arbitrary units).