Differential mRNA expression of seven genes involved in cholesterol metabolism and transport in the liver of atherosclerosis-susceptible and -resistant Japanese quail strains

Table 5 - Liver mRNA expressions ^§ in 6-week old and 12-week old SUS and RES quail fed the regular diet

Gene	Effect	6-week old		12-week old
Gene	Effect	RES (N = 7)	SUS (N = 6)	RES (N = 6)	SUS (N = 6)
HMGCR	*P < 0.02	1.110 ± 0.110	0.688 ± 0.110	1.009 ± 0.110	0.864 ± 0.110
FDFT1	*P < 0.01	1.359 ± 0.217	0.558 ± 0.217	1.082 ± 0.217	0.638 ± 0.217
DHCR7	†P < 0.01	1.423 ± 0.250	1.359 ± 0.250	0.995 ± 0.250	0.829 ± 0.250
SQLE	*P < 0.02	2.430 ± 0.483	0.414 ± 0.522	1.026 ± 0.522	0.370 ± 0.522
ABCG5	*†P < 0.0005	0.594 ± 0.076b	0.547 ± 0.082b	1.288 ± 0.082a	0.586 ± 0.082b
ABCG8	*P < 0.01; † P < 0.01	0.724 ± 0.189	0.531 ± 0.204	1.654 ± 0.204	0.687 ± 0.204
APAO1	†P < 0.0001	0.626 ± 0.093	0.448 ± 0.101	1.126 ± 0.101	1.123 ± 0.101

N = number of individuals measured; total number of individuals = 25; *denotes significant strain effect; †denotes significant age effect; *†denotes significant strain x age interaction; ^§all values (± SEM) indicate the gene of interest relative to GAPDH (arbitrary units).

ISSN: 1297-9686