| |
Prior specification
|
Posterior mean (sd) of
| | |
|---|
|
Chain
|
p
0
|
b
(a)
|
N
Q
|
α
|
|
σ
2
|
hM2
(b)
|
N
Q
|
|---|
|
A
|
0.99
|
0.01
|
58.9
|
2.0 (0.6)
|
1.7 (1.2)
|
3.0 (0.1)
|
0.32 (0.02)
|
23.0 (2.5)
|
|
B
|
0.99
|
0.01
|
58.9
|
2.6 (0.7)
|
1.7 (1.2)
|
3.0 (0.1)
|
0.32 (0.02)
|
22.9 (2.6)
|
|
C
|
0.99
|
0.001
|
58.9
|
2.3 (0.5)
|
3.0 (1.9)
|
3.0 (0.1)
|
0.30 (0.02)
|
31.5 (2.5)
|
|
D
|
0.99
|
0.001
|
58.9
|
2.6 (0.5)
|
3.0 (1.9)
|
3.0 (0.1)
|
0.29 (0.02)
|
31.1 (2.5)
|
|
E
|
0.999
|
0.01
|
5.9
|
2.1 (0.5)
|
1.9 (1.3)
|
3.0 (0.1)
|
0.31 (0.02)
|
15.3 (1.3)
|
|
F
|
0.999
|
0.01
|
5.9
|
2.8 (0.5)
|
2.1 (1.4)
|
3.0 (0.1)
|
0.31 (0.02)
|
14.3 (1.3)
|
|
G
|
0.999
|
0.001
|
5.9
|
1.9 (0.4)
|
3.9 (2.3)
|
3.1 (0.1)
|
0.28 (0.02)
|
21.5 (1.4)
|
|
H
|
0.999
|
0.001
|
5.9
|
2.0 (0.7)
|
3.7 (2.2)
|
3.1 (0.1)
|
0.28 (0.02)
|
22.6 (1.8)
|
- (a) given in units of phenotypic standard deviations (sd(Y)=2.10).
- (b) The true overall heritability of the trait is 0.30 [19].
- Hyper-parameter p0 defines the prior probability that the effect size lies in the interval of the spike, (−b,b). N
Q
is a summary statistic for the number of QTL (see text for details), α the common intercept in the regression, the variance component of the polygenic terms, σ2 the residual variance, and the part of the heritability due to marker effects.
