Figure 1

Imputation accuracy by SNP (r SNP ) plotted against the minor allele frequency (MAF) for each scenario. Imputation accuracy was defined as the correlation of true genotypes with imputed genotype dosages by SNP and was calculated across 10 replicates (2000 SNPs × 10 replicates) for scenario Real (A), SireMGS (B), Off0 (C), Off1 (D), Off2 (E), and Off4 (F). The blue curves were obtained by fitting a nonparametric local regression (LOESS).