Identification of genomic regions associated with inbreeding depression in Holstein and Jersey dairy cattle

Table 4 Effect on milk production traits and fertility in Holstein and Jersey populations of increasing inbreeding by 1%

Breed	Trait	Pedigree¹		Genotyped²
		Ped_F³		Ped_F		GRM_F⁴
		b⁵(s.e.)	-log10 (P-value)	b (s.e.)	-log10 (P-value)	b (s.e.)	-log10 (P-value)
Holstein	Milk (L)	-21.1 (1.5)	45.2	-11.3 (8.8)	0.7	-27.8 (5.7)	5.9
	Fat (kg)	-0.73 (0.06)	33.4	-0.67 (0.36)	1.2	-1.28 (0.23)	7.3
	Protein (kg)	-0.63 (0.05)	37.2	-0.33 (0.29)	0.6	-0.93 (0.19)	5.9
	Calving interval (d)	0.18 (0.05)	4.4	0.12 (0.26)	0.2	0.22 (0.17)	0.69
Jersey	Milk (L)	-12.0 (2.4)	6.4	-9.4 (7.1)	0.8	-27.2 (5.2)	6.8
	Fat (kg)	-0.62 (0.12)	7.0	-0.65 (0.36)	1.2	-1.58 (0.26)	8.6
	Protein (kg)	-0.45 (0.08)	6.7	-0.39 (0.26)	0.9	-1.09 (0.19)	7.7
	Calving interval (d)	0.14 (0.09)	0.8	-0.32 (0.28)	0.6	-0.08 (0.22)	0.2

Pedigree¹: Population with pedigree information only; ²Genotyped²: Population with pedigree and genomic information; Ped_F³: pedigree inbreeding; GRM_F⁴: genomic inbreeding, defined as the diagonal of the GRM - 1; b⁵: effect of a 1% increase in inbreeding and associated standard errors (s.e.) for Holstein and Jersey populations for milk, fat and protein yields and calving interval as a measure of fertility.

ISSN: 1297-9686