Table 1 Cumulative response to selection (95 % confidence interval) relative to genomic selection only (GS only) across 20 generations of future breeding based on GS only or genomic selection plus the promotion of alleles by genome editing (GS + PAGE) when different numbers of sires and different numbers of QTN per sire were edited
Sires edited | Number of edits per sire | ||||
|---|---|---|---|---|---|
0 (GS only) | 1 (1 QTNe) | 5 (5 QTNe) | 10 (10 QTNe) | 20 (20 QTNe) | |
Bottom 10 (B10se) | 1.00 | 1.04 (1.03–1.05) | 1.23 (1.20–1.26) | 1.46 (1.41–1.50) | 1.89 (1.82–1.95) |
Top 10 (T10se) | 1.04 (1.03–1.05) | 1.23 (1.20–1.26) | 1.46 (1.41–1.50) | 1.89 (1.82–1.95) | |
All 25 (A25se) | 1.08 (1.06–1.09) | 1.31 (1.28–1.35) | 1.56 (1.51–1.61) | 2.00 (1.93–2.08) | |