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Table 2 Cumulative response to selection (95 % confidence interval) relative to genomic selection only (GS only) across 20 generations of future breeding based on GS only or genomic selection plus the promotion of alleles by genome editing (GS + PAGE) when the genome editing resources per generation were limited

From: Potential of promotion of alleles by genome editing to improve quantitative traits in livestock breeding programs

Sires edited Number of edits per generation
0 (GS only) 125 (25 QTNe) 250 (50 QTNe) 500 (100 QTNe)
Top 5 (T5se) 1.00 1.96 (1.89–2.04) 2.83 (2.71–2.96) 4.12 (3.95–4.29)
All 25 (A25se) 1.31 (1.28–1.35) 1.56 (1.51–1.61) 2.00 (1.93–2.08)
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