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Table 1 SNPs on OAR6 showing significant association with body weight in 1743 Merino sheep

From: Genome-wide association study of body weight in Australian Merino sheep reveals an orthologous region on OAR6 to human and bovine genomic regions affecting height and weight

SNP Position Adjusted P-value n0 n1 n2 p q vg β (kg)
OAR6_41936490.1 37694563 1.15 × 10−11 119 706 918 0.271 0.729 6.17 2.116
s17946.1 37164383 3.88 × 10−09 83 630 1030 0.228 0.772 5.88 −2.132
OAR6_41877997.1 37640732 1.21 × 10−07 110 650 983 0.250 0.750 6.05 −1.876
OAR6_41003295.1 36819342 1.17 × 10−06 150 722 871 0.293 0.707 6.50 −1.741
OAR6_42945420.1 38567455 1.56 × 10−05 22 321 1400 0.105 0.895 6.54 2.28
OAR6_40449774.1 36234302 3.87 × 10−04 20 378 1345 0.120 0.880 6.62 −2.079
OAR6_41558126.1 37334387 5.45 × 10−04 79 574 1090 0.210 0.790 6.30 1.686
OAR6_40409402.1 36192023 1.61 × 10−03 9 254 1480 0.078 0.922 6.65 2.337
OAR6_40370293.1 36155169 1.65 × 10−03 110 641 992 0.247 0.753 6.25 −1.589
OAR6_42247197.1 37987281 1.97 × 10−03 60 512 1171 0.181 0.819 6.52 −1.645
OAR6_40724811_X.1 36522166 3.61 × 10−03 18 385 1340 0.121 0.879 6.26 −1.914
OAR6_40855809.1 36655091 5.65 × 10−03 53 448 1242 0.159 0.841 6.34 1.612
OAR6_41768532.1 37533664 9.01 × 10−03 64 521 1158 0.186 0.814 6.46 1.542
  1. Thirteen SNPs on OAR6 reach the genome-wide significance level (adjusted P-value < 0.01). These SNPs span the region between 36.15 and 38.56 Mb. A total of 45 SNPs on the Illumina Ovine SNP50 BeadChip are mapped to this region and 30 were identified as significant for an unadjusted p-value threshold of 0.001. n0, n1, and n2 are the number of individuals with 2, 1 and 0 copies of the minor allele; p is the minor allele frequency and q = 1 – p; Vg indicates the proportion of the genetic variance that is attributable to each SNP estimated by ASReml (note that SNPs are not unlinked and the sum of effects will be overestimated). β is the allele substitution effect. SNP positions are based on the Oar_v3.1 assembly of the ovine genome sequence