Genome-wide association studies for feed intake and efficiency in two laying periods of chickens

Table 2 SNPs significantly associated with daily feed intake detected in both univariate and bivariate GWAS analyses

SNP	GGA^a	Position	P value^b	MAF^c	β^d		Candidate/nearest gene	Location (kb)^e
SNP	GGA^a	Position	P value^b	MAF^c	FI1	FI2	Candidate/nearest gene	Location (kb)^e
rs317812130	1	169,231,399	9.22e−8	0.37 (A/G)	−0.26	−0.25	RNASEH2B	Intron 9
rs318027552	1	169,613,334	1.86e−7	0.34 (A/G)	−0.25	−0.24	ATP7B	D 3.41
rs315069556	1	170,920,135	2.60e−7	0.41 (A/G)	−0.24	−0.28	UFM1	U 38.06
rs315653292	1	170,954,280	2.11e−7	0.42 (G/A)	−0.24	−0.28	ENSGALT00000042093	U 63.24
rs315827967	1	170,989,520	2.11e−7	0.42 (C/A)	−0.24	−0.28	ENSGALT00000042093	U 98.48
rs312584320	1	170,993,003	2.11e−7	0.42 (C/T)	−0.24	−0.28	ENSGALT00000042093	U 101.96
rs314667377	1	171,044,869	2.45e−7	0.41 (A/C)	−0.24	−0.28	TRPC4	U 57.64
rs315187709	1	171,548,178	1.29e−7	0.40 (A/G)	−0.23	−0.27	FAM48A	U 26.65

^aChicken chromosome
^b P values are obtained from averages across the univariate and bivariate GWAS analyses
^cAllele frequency of the first listed marker
⁴Effect of allele substitution obtained from averages across the univariate and bivariate GWAS analyses; FI1 and FI2 represent daily feed intake in laying period between 37 and 40 weeks and between 57 and 60 weeks, respectively
^eU and D indicate that the SNP is upstream and downstream of a gene, respectively

ISSN: 1297-9686