Genome-wide association studies for feed intake and efficiency in two laying periods of chickens

Table 4 SNPs significantly associated with residual feed intake and feed conversion ratio detected in the bivariate GWAS analysis

Traits^a	SNP	GGA^b	Position	P value	MAF^c	β^d		Candidate/nearest gene	Location (kb)^e
Traits^a	SNP	GGA^b	Position	P value	MAF^c	T1	T2	Candidate/nearest gene	Location (kb)^e
RFI	rs312274422	3	79,252,286	3.77e−10	0.28 (G/T)	−0.24	10.06	HTR1B	U 239.93
	rs315604099	15	3,307,271	5.29e−7	0.27 (A/G)	−0.08	9.01	RIMBP2	Intron 15
	rs312873273	17	1,366,852	1.44e−11	0.21 (G/C)	−1.90	10.49	RGS3	Intron 14
	rs315868235	23	5,055,731	1.62e−7	0.03 (C/T)	−0.46	−23.68	TMEM39B	U 0.34
FCR	rs14841309	1	68,353,988	3.57e−7	0.40 (G/C)	−0.01	−0.21	PPFIBP1	U 3.10
	rs13880743	1	66,797,959	4.40e−7	0.46 (G/A)	0.09	−0.13	ST8SIA1	Intron 3
	rs15303811	1	67,832,808	4.92e−7	0.45 (T/C)	0.03	−0.18	ITPR2	Intron 54
	rs317525285	1	66,971,254	6.18e−7	0.39 (A/T)	0.05	−0.17	C3AR1	D 27.52
	rs13882373	1	68,400,729	6.26e−7	0.46 (A/T)	−0.11	0.11	PPFIBP1	Intron 4
	rs314631602	1	68,131,791	6.67e−7	0.44 (A/T)	0.07	−0.15	C1H12orf11	Intron 2
	rs317881125	1	67,475,629	6.82e−7	0.17 (T/A)	−0.16	0.14	LOC418209	D 34.44
	rs315936100	1	67,956,079	7.74e−7	0.50 (A/G)	−0.11	0.11	ITPR2	Intron 27

^aRFI and FCR represent residual feed intake and feed conversion ratio, respectively
^bChicken chromosome
^cAllele frequency of the first listed marker
^dEffect of allele substitution; T1 and T2 represent laying periods between 37 and 40 weeks and between 57 and 60 weeks, respectively
^eU and D indicate that the SNP is upstream and downstream of a gene, respectively

ISSN: 1297-9686