The use of genomic coancestry matrices in the optimisation of contributions to maintain genetic diversity at specific regions of the genome

Table 3 Average rate of genomic coancestry in genomic regions targeted for minimising coancestry and in the rest of the genome across generations (t), when applying different management strategies (CHR, CHR_{_ove}, REG, REG_{_ove}) for a population of size 20

t	CHR	CHR_{_ove}		REG	REG_{_ove}
t	CHR	C = 1.0 %	C = 0.1 %	REG	C = 1.0 %	C = 0.1 %
Rate of genomic coancestry at regions targeted for minimisation (%)
1	−4.64	−4.33	−3.79	−2.18	−2.06	−1.78
2	−1.08	−1.09	−0.54	−0.39	−0.64	−0.16
3	−0.06	−0.28	−0.22	−0.33	−0.32	−0.05
4	−0.06	0.14	0.04	−0.25	0.23	0.09
5	0.30	0.22	0.14	0.10	0.25	0.23
10	0.42	0.37	0.35	0.54	0.35	0.40
Rate of genomic coancestry at the rest of genome (%)
1	6.28	2.27	1.47	3.86	2.42	1.67
2	4.34	2.44	1.52	3.22	2.26	1.59
3	4.20	2.32	1.40	3.31	2.32	1.61
4	4.04	2.38	1.50	3.05	2.46	1.59
5	3.82	2.37	1.48	2.98	2.30	1.67
10	3.28	2.40	1.40	2.81	2.25	1.45

Two different constraints (C) were imposed on the rate of coancestry at the rest of the genome when applying strategies CHR_{_ove} and REG_{_ove}
CHR contributions are optimised to minimise f _{m_chr}, CHR _{_ove} contributions are optimised to minimise f _{m_chr} while restricting f _{m_ove-chr}, REG contributions are optimised to minimise f _{m_reg}, REG _{_ove} contributions are optimised to minimise f _{m_reg} while restricting f _{m_ove-reg}

ISSN: 1297-9686