A simple strategy for managing many recessive disorders in a dairy cattle breeding program

Table 1 Properties of the recessive loci included in each scenario simulated

Group	Scenario^a	N^b	Recessive loci
Group	Scenario^a	N^b	Frequency	Value ($)^c	Name	Lethal
Holstein	All recessive loci	12	0.0276	150	Brachyspina	Yes
			0.0192	40	HH1	Yes
			0.0166	40	HH2	Yes
			0.0295	40	HH3	Yes
			0.0037	40	HH4	Yes
			0.0222	40	HH5	Yes
			0.0025	150	BLAD	Yes
			0.0137	70	CVM	Yes
			0.0001	40	DUMPS	Yes
			0.0007	150	Mulefoot	Yes
			0.9929	40	Horned	No
			0.0542	−20	Red coat color	No
	All recessive loci, high cost	12	0.0276	450	Brachyspina	Yes
			0.0192	120	HH1	Yes
			0.0166	120	HH2	Yes
			0.0295	120	HH3	Yes
			0.0037	120	HH4	Yes
			0.0222	120	HH5	Yes
			0.0025	450	BLAD	Yes
			0.0137	210	CVM	Yes
			0.0001	120	DUMPS	Yes
			0.0007	450	Mulefoot	Yes
			0.9929	120	Horned	No
			0.0542	−60	Red coat color	No
Hypothetical	High frequency, low value	1	0.90	20	High, low	Yes
	High frequency, high value	1	0.90	200	High, high	Yes
	Medium frequency, low value	1	0.50	20	Medium, low	Yes
	Medium frequency, high value	1	0.50	200	Medium, high	Yes
	Low frequency, low value	1	0.01	20	Low, low	Yes
	Low frequency, high value	1	0.01	200	Low, high	Yes
	All recessive loci	6	As above
Horned	Horned locus, market value	1	0.9929	40	Horned	No
	Horned locus, high value	1	0.9929	400	Horned	No

ISSN: 1297-9686