Multi-omic data integration and analysis using systems genomics approaches: methods and applications in animal production, health and welfare

Table 1 Overview of the different ‘omic’ levels used in systems genomic analyses

	Description	References
Genome	Complete collection of DNA, containing all the genetic information of an organism	[5]
Epigenome	Complete collection of changes to the DNA and histone proteins	[6]
Transcriptome	Complete collection of RNA molecules in a cell or collection of cells	[7]
Proteome	Complete collection of proteins in e.g. a cell, tissue, or organism	[8]
Metabolome	Complete collection of small-molecule chemicals (e.g. hormones) in e.g. a cell, tissue or organism	[9–11]
Microbiome	Complete collection of (genes of) microbes in the organism	[12]
Metagenome	Complete collection of genetic material contained in an environmental sample	[13]
Phenome	Complete collection of phenotypic traits, affected by genomic and/or environmental factors in an organism	[14, 15]
Functome	Complete collection of functions described by all the complementary members in living organisms	[16, 17]

ISSN: 1297-9686