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Table 3 List of QTL and genome-wide significant SNPs identified by QTL mapping (LDLA) and GWAS

From: Detection of QTL for traits related to adaptation to sub-optimal climatic conditions in chickens

Trait

GGA

Loc (M)

CI (M)

MLR

Nearest SNPs

SL

QTL effect

GWAS

Published related QTL

BW00

1

3.452

3.442–3.462

124.22

GGaluGA046916-rs13947322

G***

0.269

–

BW

BW00

2

0.831

0.821–0.841

74.46

rs14168592-rs14170121

G*

0.251

–

BW

BW04

2

2.341

2.331–2.351

60.68

rs14234623-rs16106127

C*

0.498

–

BW

BW08

2

2.341

2.331–2.351

71.7

rs14234623-rs16106127

C**

0.748

–

BW

BW16

2

2.341

2.331–2.351

82.98

rs14234623-rs16106127

G**

0.720

 

BW

SL08

2

2.341

2.331–2.351

63.31

rs14234623-rs16106127

C*

0.486

–

BW

SRBC00

2

0.111

0.101–0.141

60.69

GGaluGA131350-rs14134125

C*

0.431

–

BW

BW12

3

0.06

0.05–0.07

65.9

rs14308283-GGaluGA203599

C**

0.399

–

BW

BW16

3

0.03

0.02–0.07

62.52

GGaluGA203198-GGaluGA203599

C*

0.345

–

BW

CA16

3

0.02

0.01–0.03

66.44

rs14309145-rs14308726

C**

0.280

–

BW

BW00

4

1.141

1.131–1.151

77.01

GGaluGA258962-rs14469696

G*

0.787

–

BW,IM

SRBC14

4

1.391

1.381–1.401

63.77

rs14480306-GGaluGA262668

C**

0.622

–

BW

CA16

5

0.231

0.221–0.241

60.79

rs14511113-rs15655840

C**

0.426

–

IM

SL08

5

0.611

0.601–0.621

54.24

GGaluGA278486-rs14521985

C*

0.343

–

BW

BW04

7

0.732

0.722–0.742

60.69

rs16596997-rs15864433

C**

0.514

–

BW

SL08

7

0.712

0.702–0.732

58.74

GGaluGA315581-GGaluGA316229

C*

0.221

–

BW

BW00

9

0.774

0.764–0.784

139.65

GGaluGA342923-rs16677966

G***

0.449

–

BW,IM

SL08

12

0.103

0.093–0.113

57.16

rs13621525-GGaluGA082232

C*

0.469

–

BW

SRBC00

12

0.403

0.393–0.413

55.25

rs14040595-GGaluGA085745

C*

0.385

–

BW

SL08

13

0.077

0.067–0.087

52.39

rs14057266-GGaluGA091278

C*

0.421

–

BW

SRBC00

13

0.317

0.307–0.327

54.13

GGaluGA094109-rs15001109

C*

0.496

–

BW

BW04

14

0.131

0.121–0.141

108.62

rs15722248-rs15723606

G***

0.526

–

BW,IM

BW08

14

0.171

0.151–0.181

69.68

rs14071741-GGaluGA100621

C**

0.453

–

BW

SL08

14

0.171

0.161–0.181

64.13

rs13531412-GGaluGA100621

C*

0.188

–

BW

SRBC14

14

–

–

–

–

–

–

1 G-W SNP (7418129 bp)

–

BW16

17

0.277

0.257–0.287

51.51

rs15799059-rs14100782

C*

0.567

–

BW

CA16

17

0.137

0.127–0.147

50.45

rs15033487-GGaluGA113549

C*

0.310

–

BW

SRBC00

17

0.197

0.187–0.207

62.72

rs15032558-rs14102021

C**

0.363

–

BW

SRBC07

18

0.412

0.402–0.422

49.89

rs13509086-GGaluGA122291

C*

0.177

–

–

SRBC14

18

0.412

0.402–0.422

50.99

rs13509086-GGaluGA122291

C*

0.442

–

–

SRBC14

19

0.151

0.141–0.161

56.17

rs13573938-rs14118340

C**

0.349

–

BW

BW12

20

0.381

0.371–0.391

52.76

rs16005422-rs16172318

C*

0.446

–

BW

SL08

20

0.381

0.371–0.391

51.38

rs16005422-rs16172318

C*

0.233

–

BW

SRBC00

21

0.3

0.29–0.33

55.45

rs16180505-GGaluGA184295

C*

0.289

–

–

BW04

24

0.291

0.281–0.301

53.35

rs16196993-GGaluGA192626

C*

0.214

13 G-W SNPs (4145811–5321244 bp)

BW

BW08

24

–

–

–

–

–

–

7 G-W SNPs (4286369–6019223 bp)

–

CA16

24

0.281

0.271–0.291

54.07

GGaluGA192284-rs14295712

C*

0.325

–

BW

CA16

26

0.385

0.375–0.395

52.51

rs14300692-rs16204214

C*

0.182

–

BW

BW00

27

0.461

0.451–0.471

117.61

GGaluGA200219-rs14304325

G***

0.402

–

BW,IM

BW00

28

0.203

0.193–0.213

49.59

GGaluGA201613-GGaluGA201725

C*

0.556

–

BW,IM

BW04

Z

0.43

0.41–0.44

166.33

rs14756962-rs16763234

G***

0.893

50 G-W SNPs (11113817–17739555 bp)

IM

BW08

Z

0.38

0.36–0.39

294.24

rs14786654-rs16102663

G***

1.409

119 G-W SNPs (9581584–21954151 bp)

BW,IM

BW0804

Z

0.38

0.36–0.39

288.44

rs14786654-rs16102663

G***

1.323

136 G-W SNPs (9088090–21954151 bp)

BW,IM

BW12

Z

0.38

0.36–0.39

226.51

rs14786654-rs16102663

G***

1.712

99 G-W SNPs (10983124–21146543 bp)

BW,IM

BW1208

Z

–

–

–

–

–

–

17 G-W SNPs (11327074–17739555 bp)

–

BW16

Z

0.37

0.35–0.39

216.29

rs16131361-rs16102663

G***

1.773

121 G-W SNPs (4646914–21954151 bp)

BW,IM

BW1612

Z

0.32

0.31–0.33

75.71

GGaluGA347787-rs16780992

C*

1.158

20 G-W SNPs (8872779–15196080 bp)

–

CA16

Z

1.1

1.09–1.13

82.4

rs16109845-rs16768163

C*

0.615

–

BW,IM

SL08

Z

0.37

0.36–0.39

367.79

rs14786654-rs16102663

G***

2.250

131 G-W SNPs (2937208–115665705 bp)

BW,IM

SRBC07

Z

0.6

0.59–0.61

79.81

rs16100247-GGaluGA349037

C*

0.756

–

IM

  1. GGA: Gallus gallus chromosome; Loc: location; CI: confidence interval; MLR: maximal likelihood ratio; SL: significance level with C*, C**, and C*** at 5, 1, and 0.1% chromosome-wide significance and G*, G**, and G*** at 5, 1, and 0.1% Bonferroni genome-wide (G-W) significance, respectively; QTL effect: substitution effect expressed in residual standard deviation; GWAS: chromosomal region detected by GEMMA; BW00, 04, 08, 12, 16: body weight at hatch, at 4, 8, 12, and 16 weeks of age; BW0804, 1612: body weight gain during 4 to 8 weeks of age and 12 to 16 weeks of age; CA16: size of comb area at 16 weeks of age; SL08: shank length at 8 weeks of age; SRBC00, 07, 14: baseline antibody level, antibody level at 7 and 14 days after primary immunization of sheep red blood cell; Published related QTL: QTL regions that were detected in the current study and overlapped with published related QTL (BW: overlapped with body weight, shank length, or egg weight QTL; IM: overlapped with immune related QTL