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Fig. 3 | Genetics Selection Evolution

Fig. 3

From: Combined GWAS and ‘guilt by association’-based prioritization analysis identifies functional candidate genes for body size in sheep

Fig. 3

Depiction of a network with connections of the top 20 prioritized genes. The network is comprised of 1190 nodes, 1430 edges and 16 seed proteins. Genes are shown in yellow (OAR11), blue (OAR25), green (OAR9) or magenta (OAR3). White colors represent connected genes and edges number of associations. Network analysis was performed via the web application NetworkAnalyst [64–66] and the network interactome database innateDB [67] comprising literature curated comprehensive protein–protein interaction (PPI) data (~140,000 interactions) [68]. Here, genes were prioritized using the degree of centrality

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Genetics Selection Evolution

ISSN: 1297-9686