A model to estimate effects of SNPs on host susceptibility and infectivity for an endemic infectious disease

Table 1 Relationship between the transmission rate parameters and the regression coefficients of the generalized linear mixed model for each genotype

Transmission rate parameter^a	Expression in terms of regression coefficients
β _ggff	\(e^{{c_{0} }}\)
β _Ggff	\(e^{{c_{0} + c_{1} }}\)
β _GGff	\(e^{{c_{0} + 2c_{1} }}\)
β _ggFf	\(e^{{c_{0} + c_{2} }}\)
β _GgFf	\(e^{{c_{0} + c_{1} + c_{2} }}\)
β _GGFf	\(e^{{c_{0} + 2c_{1} + c_{2} }}\)
β _ggFF	\(e^{{c_{0} + 2c_{2} }}\)
β _GgFF	\(e^{{c_{0} + c_{1} + 2c_{2} }}\)
β _GGFF	\(e^{{c_{0} + 2c_{1} + 2c_{2} }}\)

^aThe first two subscripts of β indicate the susceptible genotype of susceptible individuals, the second two subscripts indicate the infectivity genotype of infectious individuals. It follows that \(\gamma_{G} = e^{{c_{1} }}\) and \(\varphi_{F} = e^{{c_{2} }}\)

ISSN: 1297-9686