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Table 4 Estimates of the effect of infectivity, bias, precision, power, and error caused by the geometric mean approximation (GMA)

From: A model to estimate effects of SNPs on host susceptibility and infectivity for an endemic infectious disease

Input (\(\varphi_{f}\) − \(\varphi_{F}\))a

Estimate (\(\varphi_{f} - \hat{\varphi }_{F}\))a

Bias

RMSE

Power (%)

GMA errorb

Absolute

Relative (%)

0.0

−0.011

−0.011

−1.1

0.215

2.0

−0.0002

0.1

0.029

−0.071

−71.4

0.212

5.0

0.0001

0.2

0.125

−0.075

−37.5

0.191

10.5

0.0005

0.3

0.197

−0.103

−34.3

0.185

23.0

0.0008

0.4

0.279

−0.121

−30.2

0.203

44.0

0.0017

0.5

0.350

−0.150

−30.0

0.222

60.0

0.0029

0.6

0.449

−0.151

−25.2

0.200

80.0

0.0052

0.7

0.529

−0.171

−24.5

0.203

90.5

0.0082

  1. Precision was measured by RMSE and results are averages of 200 replicates
  2. a \(\varphi_{f}\) = 1
  3. b \(\hat{\varphi }_{F} - \hat{\varphi }_{{F_{corrected \, for \, GMA} }}\)