A model to estimate effects of SNPs on host susceptibility and infectivity for an endemic infectious disease

Table 5 Precision, power, and error caused by the geometric mean approximation (GMA) for different recording intervals

Recording interval % infectious time	RMSE		Power		GMA error^a
Recording interval % infectious time	Susceptibility	Infectivity	Susceptibility (%)	Infectivity (%)	GMA error^a
4.8	0.042	0.294	100.0	47.0	0.0154
9.5	0.031	0.203	100.0	65.5	0.0133
14.3	0.025	0.178	100.0	75.5	0.0115
19.0	0.022	0.147	100.0	80.5	0.0105
23.8	0.020	0.152	100.0	80.5	0.0090
28.6	0.021	0.144	100.0	83.0	0.0088
33.3	0.022	0.163	100.0	84.5	0.0088
38.1	0.023	0.141	100.0	86.0	0.0080
42.9	0.026	0.158	100.0	84.0	0.0076
47.6	0.030	0.151	100.0	88.5	0.0074
52.4	0.034	0.179	100.0	85.5	0.0061
57.1	0.037	0.193	100.0	78.5	0.0053
61.9	0.042	0.213	100.0	81.5	0.0055
66.7	0.046	0.200	100.0	80.5	0.0052
71.4	0.046	0.200	100.0	82.5	0.0052
76.2	0.055	0.220	100.0	77.0	0.0045
81.0	0.059	0.219	100.0	79.5	0.0042
85.7	0.063	0.238	100.0	77.0	0.0041
90.5	0.069	0.241	100.0	75.5	0.0037
95.2	0.071	0.263	100.0	72.0	0.0032
100.0	0.076	0.268	100.0	65.0	0.0033
104.8	0.079	0.313	100.0	73.0	0.0028
109.5	0.083	0.301	100.0	68.5	0.0030
114.3	0.088	0.278	100.0	69.0	0.0028
119.1	0.089	0.301	100.0	66.0	0.0026
123.8	0.094	0.317	100.0	60.5	0.0024
128.6	0.096	0.320	100.0	66.0	0.0022
133.3	0.099	0.322	100.0	60.0	0.0023

Precision was measured by RMSE and results are averages of 200 replicates. Further inputs are in Table 2, Scenario 2
^a \(\hat{\varphi }_{F} - \hat{\varphi }_{{F_{corrected for GMA} }}\)

ISSN: 1297-9686