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Table 2 Candidate genes for domestication loci in Asia and Europe

From: Genome-wide SNP data unveils the globalization of domesticated pigs

Region

Chr

Position

Fst

Rank

Location

Genes

Notes

Asia

15

105803885

0.90

1

Intergenic

MSTN

Muscle growth/differentiation [33]

 

14

51279090

0.81

2

Intergenic

PATZ1

Spermatogenesis [41]

 

5

23737420

0.80

6

In gene

LEP

Growth, energy homeostasis [35]

 

4

90358483

0.80

7

In exon

TBX19

Personality traits angry/hostility [37]

 

6

45563650

0.78

8

Intergenic

PAFAH1B3

Development of brain [38]

 

6

45609490

0.76

11

In gene

GSK3A

Insulin signaling pathways [36]

 

8

58493225

0.75

14

Intergenic

NMU

Food intake and energy balance [34]

 

8

69912174

0.72

20

In exon

GNRHR

Pubertal delay [39]

 

1

16779942

0.70

27

In gene

ESR1

Precocious puberty [40]

 

2

12631241

0.70

29

In gene

Olfr466

Perception of smell [42]

Europe

18

21362149

0.74

1

Intergenic

LRRC4

Central nervous system [48]

 

13

105334978

0.74

2

In gene

VEPH1

Central nervous system [49]

 

13

94430998

0.71

3

In gene

PLSCR4

Reproduction [52]

 

18

42219500

0.69

5

Intergenic

TBX20

Cardiac LDL-cholesterol [44]

 

4

46284264

0.69

6

Intergenic

TMEM67

Protein catabolic process [45]

 

7

67285122

0.68

7

Intergenic

FOXA1

Glucose homeostasis [46]

 

10

12907670

0.65

15

In gene

SOX2-OT

Vertebrate development [43]

 

16

15192108

0.65

16

Intergenic

CDH9

Autism spectrum disorder [50]

 

6

53526888

0.64

18

Intergenic

LAIR1

Immune response [51]

 

15

27308675

0.64

19

Intergenic

INSIG2

Cholesterol synthesis [47]