Detection of two non-synonymous SNPs in SLC45A2 on BTA20 as candidate causal mutations for oculocutaneous albinism in Braunvieh cattle

Table 3 Albinism genes

Type of albinism	Locus	Position (UMD 3.1, ENSEMBL)
Oculocutaneous albinism type 1	TYR	BTA29: 6,351,877–6,462,240
Oculocutaneous albinism type 2	OCA2	BTA2: 347,042–598,104
Oculocutaneous albinism type 3	TYRP1	BTA8: 31,710,698–31,726,956
Oculocutaneous albinism type 4	SLC45A2	BTA20: 39,829,673–39,867,694
Hermansky-Pudlak Syndrome type 1	HPS1	BTA26: 19,361,232–19,386,569
Hermansky-Pudlak Syndrome type 2	AP3B1	BTA10: 9,040,253–9,300,567
Hermansky-Pudlak Syndrome type 3	HPS3	BTA1: 119,944,594–119,985,509
Hermansky-Pudlak Syndrome type 4	HPS4	BTA17: 68,368,661–68,396,020
Chediak-Higashi Syndrome	LYST	BTA28: 8,423,715–8,567,655
Ocular albinism type 1	GPR143	BTAX: 143,861,798–143,891,357

Genes causing albinism according to the albinism database provided by the University of Minnesota (http://www.ifpcs.org/albinism/) and their positions in the cattle genome. The position highlighted in italics was included in one of the candidate haplotypes given in Table 2

ISSN: 1297-9686