Fig. 8

Number of haplotypes sequenced at (or above) the target coverage of 10× (filled section) using three different approaches to handle the rare haplotypes: to include all singletons and doubletons, to exclude all singletons and doubletons, or to filter them based on flanking context. Numbers are shown by haplotype population count and for different amounts of sequencing resources. The number of singletons and doubletons for each approach were 3971, 0, and 953, respectively