Table 2 Significantly enriched annotation clusters and functional terms
From: Genomic selection signatures in sheep from the Western Pyrenees
Annotation cluster 1 | Enrichment score: 4.6 | ||
|---|---|---|---|
Category | Term | Genes | Corrected P value |
SCR group B | |||
GOTERM_MF_DIRECT | GO:0045028: G-protein coupled purinergic nucleotide receptor activity | P2RY12, P2RY13, P2RY14, GPR171, GPR87 | 3.7 × 10−7 |
GOTERM_BP_DIRECT | GO:0035589: G-protein coupled purinergic nucleotide receptor signaling pathway | P2RY12, P2RY13, P2RY14, GPR171, GPR87 | 1.3 × 10−6 |
GOTERM_CC_DIRECT | GO:0005887: integral component of plasma membrane | P2RY12, P2RY13, P2RY14, SLMAP, GPR171, PKD2, GPR87 | 0.790 |
GOTERM_BP_DIRECT | GO:0007186: G-protein coupled receptor signaling pathway | P2RY12, P2RY14, GPR171 | 1.000 |
Annotation cluster 1 | Enrichment score: 2.7 | ||
|---|---|---|---|
Category | Term | Genes | Corrected P value |
SCR group C | |||
KEGG_PATHWAY | hsa04740: olfactory transduction | OR56A3, OR56A4, OR52B2, OR56A1, OR56B4, OR52L1, OR52W1, CNGA4 | 0.002 |
GOTERM_MF_DIRECT | GO:0004984: olfactory receptor activity | OR56A3, OR56A4, OR52B2, OR56A1, OR56B4, OR52L1, OR52W1 | 0.027 |
GOTERM_BP_DIRECT | GO:0050911: detection of chemical stimulus involved in sensory perception of smell | OR56A3, OR56A4, OR52B2, OR56A1, OR56B4, OR52L1, OR52W1 | 0.101 |
GOTERM_BP_DIRECT | GO:0007165: signal transduction | OR56A3, OR52B2, OR56B4, OR52L1, EVI2A, NF1, SMPD1, OR52W1, ESR1, APBB1 | 0.130 |
GOTERM_MF_DIRECT | GO:0004930: G-protein coupled receptor activity | OR56A3, OR56A4, OR52B2, OR56A1, OR56B4, OR52L1, OR52W1 | 0.163 |
GOTERM_BP_DIRECT | GO:0007186: G-protein coupled receptor signaling pathway | OR56A3, OR52B2, OR56B4, OR52L1, CCKBR, OR52W1 | 0.980 |
GOTERM_CC_DIRECT | GO:0005886: plasma membrane | OR52B2, CCKBR, MAP1B, NSFL1C, ESR1, OR56A3, OR56A4, OR56B4, OR56A1, OR52L1, SMPD1, OR52W1, MC3R, OMG, APBB1, FAM126B | 0.964 |