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Table 2 Significantly enriched annotation clusters and functional terms

From: Genomic selection signatures in sheep from the Western Pyrenees

Annotation cluster 1 Enrichment score: 4.6
Category Term Genes Corrected P value
SCR group B
GOTERM_MF_DIRECT GO:0045028: G-protein coupled purinergic nucleotide receptor activity P2RY12, P2RY13, P2RY14, GPR171, GPR87 3.7 × 10−7
GOTERM_BP_DIRECT GO:0035589: G-protein coupled purinergic nucleotide receptor signaling pathway P2RY12, P2RY13, P2RY14, GPR171, GPR87 1.3 × 10−6
GOTERM_CC_DIRECT GO:0005887: integral component of plasma membrane P2RY12, P2RY13, P2RY14, SLMAP, GPR171, PKD2, GPR87 0.790
GOTERM_BP_DIRECT GO:0007186: G-protein coupled receptor signaling pathway P2RY12, P2RY14, GPR171 1.000
Annotation cluster 1 Enrichment score: 2.7
Category Term Genes Corrected P value
SCR group C
KEGG_PATHWAY hsa04740: olfactory transduction OR56A3, OR56A4, OR52B2, OR56A1, OR56B4, OR52L1, OR52W1, CNGA4 0.002
GOTERM_MF_DIRECT GO:0004984: olfactory receptor activity OR56A3, OR56A4, OR52B2, OR56A1, OR56B4, OR52L1, OR52W1 0.027
GOTERM_BP_DIRECT GO:0050911: detection of chemical stimulus involved in sensory perception of smell OR56A3, OR56A4, OR52B2, OR56A1, OR56B4, OR52L1, OR52W1 0.101
GOTERM_BP_DIRECT GO:0007165: signal transduction OR56A3, OR52B2, OR56B4, OR52L1, EVI2A, NF1, SMPD1, OR52W1, ESR1, APBB1 0.130
GOTERM_MF_DIRECT GO:0004930: G-protein coupled receptor activity OR56A3, OR56A4, OR52B2, OR56A1, OR56B4, OR52L1, OR52W1 0.163
GOTERM_BP_DIRECT GO:0007186: G-protein coupled receptor signaling pathway OR56A3, OR52B2, OR56B4, OR52L1, CCKBR, OR52W1 0.980
GOTERM_CC_DIRECT GO:0005886: plasma membrane OR52B2, CCKBR, MAP1B, NSFL1C, ESR1, OR56A3, OR56A4, OR56B4, OR56A1, OR52L1, SMPD1, OR52W1, MC3R, OMG, APBB1, FAM126B 0.964
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Genetics Selection Evolution

ISSN: 1297-9686