Table 1 Significant (p < 1e−5) protein-altering variants and predicted impact
From: Early and late feathering in turkey and chicken: same gene but different mutations
Chr | bp | REF | ALT | P | Case/control AF | Gene | Type | Effect | Impact (PROVEAN) |
|---|---|---|---|---|---|---|---|---|---|
Z | 7,958,551 | T | C | 1.96e − 06 | 0.909/0.167 | RGP1 | Missense | Arg227Lys | Neutral (0.58) |
Z | 7,982,630 | A | G | 5.35e − 07 | 0.0833/0.833 | CREB3 | Missense | Pro178Ser | Neutral (− 1.55) |
Z | 7,982,834 | A | G | 1.96e − 06 | 0.909/0.167 | CREB3 | Missense | Val124Ile | Neutral (0.91) |
Z | 8,172,555 | T | C | 9.60e − 08 | 0.0833/0.917 | LOC104914814 | Missense | Gln47Arg | Neutral (− 0.22) |
Z | 8,181,148 | A | G | 5.35e − 07 | 0.917/0.167 | LOC100540309 | Missense | Arg157Lys | Neutral (0.90) |
Z | 8,227,879 | T | C | 5.35e − 07 | 0.0833/0.833 | LOC104914815 | Missense | Val320Ile | Neutral (− 0.07) |
Z | 9003502 | A | T | 2.60e − 09 | 0/0.833 | ADAMTS12 | Missense | Leu991Pro | Neutral (2.10) |
Z | 9426018 | G | GTTGGT | 2.60e − 09 | 1/0.167 | PRLR | Frameshift | Glu704FS | High |