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Table 6 Bias of the GEBV measured by regression slope for one random replicate in each simulation scenario and different strategies for selection of rare and low-frequency variants (RLFV)

From: Impact of rare and low-frequency sequence variants on reliability of genomic prediction in dairy cattle

Scenarios

SQTN

MQTN

LQTN

50 k

0.929

0.986

0.927

50 k + all simulated QTN

1.009

1.010

0.963

50 k + simulated QTN and RLFV from 10 random selected genes from each chromosome

0.995

1.016

0.938

50 k + RLFV in mapped genes

0.986

1.013

0.967

  1. SQTN corresponds to the scenario with RLFV in seven to ten genes per chromosome simulated as causal variants; MQTN corresponds to the scenario with RLFV in one gene per chromosome simulated as causal variants; LQTN corresponds to the scenario with RLFV in nine randomly selected genes across the whole genome simulated as causal variants