Genome-wide associations and detection of potential candidate genes for direct genetic and maternal genetic effects influencing dairy cattle body weight at different ages

Table 5 Number of significant SNPs influencing maternal genetic effects and inflation factor for body weight recorded at different ages

Trait	Dependent variable	Polygenic effect	FDR^a	Bonferroni^b	λ
BW0	mDRP	\({\mathbf{A}}\)	26	6	1.12
		\({\mathbf{G}}\)	0	0	0.99
		LOCO + CHR_PC20	0	0	0.64
		LOCO + CHR_PC3	3	0	1.00
BW23	mDRP	\({\mathbf{A}}\)	0	0	1.04
		\({\mathbf{G}}\)	0	0	0.99
		LOCO + CHR_PC20	0	0	0.59
		LOCO + CHR_PC3	0	0	0.91
BW1314	mDRP	\({\mathbf{A}}\)	0	0	1.08
		\({\mathbf{G}}\)	0	0	1.00
		LOCO + CHR_PC20	0	0	0.56
		LOCO + CHR_PC3	0	0	0.91

FDR: false discovery rate; Bonferroni: Bonferroni correction; λ: inflation factor; BW0: body weight recorded at birth; BW23: body weight recorded at 2 to 3 months of age; BW1314: body weight recorded at 13 to 14 months of age; dDRP: de-regressed proofs for the direct genetic effect; mDRP: de-regressed proofs for the maternal genetic effect
^aNumber of significant SNPs according to false discovery rate
^bNumber of significant SNPs according to Bonferroni-correction

ISSN: 1297-9686