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Fig. 7 | Genetics Selection Evolution

Fig. 7

From: Multiple QTL underlie milk phenotypes at the CSF2RB locus

Fig. 7

Left: dotplot of the sequence from the CSF2RB 3′-UTR against its complement. Positions are relative to chr5:75,747,904. Black dots indicate that seven of the 11 surrounding nucleotides are complementary. Vertical dashed red lines indicate the locations of predicted RNA-editing sites. Sections of the region 2275–2452 are complementary to the regions 837–915, 1178–1350, 1591–1719, and 1757–1832, suggesting that the UTR is able to fold into multiple configurations. Right: the section of predicted double stranded sequence between 1184 and 1217 on the left strand (running upward), and 2411–2444 on the right strand (running downward). Edited sites are coloured based on the strength of the edQTL at that site, from blue (not significant) to red (max P = 5.22 × 10−26). Sites are labelled with the correlation between the edQTL and the milk volume (MY) QTL after adjusting for marker rs208473130

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