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Table 5 Statistics for the AA14H3, CH19H2, and SI16H5 haplotypes

From: Analysis of a large dataset reveals haplotypes carrying putatively recessive lethal and semi-lethal alleles with pleiotropic effects on economically important traits in beef cattle

Haplotype AA14H3 CH19H2 SI16H5
Genotyped animals 22,510 38,960 11,559
Frequency (%) 15.2 14.4 8.8
Recessive homozygotes 95 83 0
Expected recessive homozygotes 194.1 256 47.6
Sire-carrier × dam-carrier matings 220 256 17
Recessive homozygotes from sire-carrier × dam-carrier matings 2 6 0
Expected recessive homozygotes from sire-carrier × dam-carrier matings 55 64 4.3
Sire-carrier × maternal grand-sire-carrier matings 141 87 7
Recessive homozygotes from sire-carrier × maternal grand-sire-carrier matings 0 1 0
Expected recessive homozygotes from sire-carrier × maternal grand-sire-carrier matings 17.6 10.9 0.9
Probability of not observing recessive homozygotes with the T1 testa 2.3 × 10−85 2.5 × 10−112 2.0 × 10−21
Probability of not observing recessive homozygotes with the T2 testa 3.3 × 10−28 1.0 × 10−32 7.9 × 10−3
Probability of not observing recessive homozygotes with the T3 testa 6.7 × 10−9 9.0 × 10−9 3.9 × 10−1
Probability that the observed and expected number of recessive homozygotes are not different with the T4 testa 1.1 × 10−16 1.1 × 10−16 1.7 × 10−2
Probability that the observed and expected number of recessive homozygotes are not different with the T5 testa 7.2 × 10−6 1.4 × 10−3 3.2 × 10−1
  1. aT1: population test; T2: carrier mating test on sire × dam matings; T3: carrier mating test on sire × maternal grand-sire matings; T4: semi-lethality test on sire × dam matings; T5: semi-lethality test on sire × maternal grand-sire mating
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