Table 5 Comparison of the numbers of significantly associated SNPs identified by applying an annotation category-based Bonferroni correction to each annotation category
Category | Number of significant variants | |
|---|---|---|
With conventional Bonferroni correction | With category-based Bonferroni correction | |
High impact | 9 | 10 |
Moderate impact | 208 | 226 |
Low impact | 378 | 852 |
Open chromatin | 3700 | 3661 |
No known function | 54,244 | 54,244 |
Total | 58,539 | 58,993 |