Management of lethal recessive alleles in beef cattle through the use of mate selection software

Table 1 Reported allele frequencies for recessive haplotypes in both dairy and beef cattle

Breed	Haplotype frequency (%)	Carrier frequency (%)	Functional/gene name	References
Ayrshire	13.0		PIRM/UBE3B	[9, 10]
		20	RPAP2	[11]
Belgian blue		10	MYH6	[7]
		10.2	SNAPC4	[7]
		3.8	RPIA	[7]
		2.6	EXOSC4	[7]
		2.2	MED22	[7]
Braunvieh		14		[12]
		13 (3.4)	TUBD1	[13]
Fleckvieh		2.9		[14]
		4.1	SLC2A2	[14]
		3.3		[14]
		3.3	SUGT1	[14]
Brown Swiss	6.67		–	[4]
	7.78		TUBD1	[13]
	2.19		SDM/SPAST	[15, 16]
	3.61		SMA/KDSR(FVT1)	[17, 18]
	1.56		Weaver/PNPLA8	[19, 20]
Holstein	2.76		Brachyspina/FANCI	[21, 22]
	1.92	4.5	APAF1	[23, 24]
	1.66		–	[4, 25]
	2.95	4.7	SMC2	[25, 26]
	0.37		GART	[24]
	2.22	5.5	TFB1M	[9, 27]
	0.25		BLAD/ITGB2	[28]
	1.37	8	CVM/SLC35A3	[29, 30]
	0.1		DUMPS/UMPS	[31]
Jersey	12.1	23.4	CWC15	[32]
	1.3		–	[33]
		13.2	OBFC1	[7]
Montbéliarde		18	PFAS	[34, 35]
		14	SLC37A2	[35]
Normande		3.8		[35]
Japanese black		4.8	ANXA10	[36]
Angus	7.8		GEMIN2	[6]
	15.2		ZFAT	[37]
Charolais	14.4		–	[37]
Simmental	8.8		–	[37]

Modified from Cole et al. [8] and Georges et al. [5]. Reproduced with permission via Copyright Clearance Center

ISSN: 1297-9686