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Table 5 Predicted number of homozygous offspring (aa) with standard errors (SE) for different percentages of herd genotyped in three scenariosa given two selection strategiesb

From: Management of lethal recessive alleles in beef cattle through the use of mate selection software

Level of genotyping

% Herd genotyping

Predicted number of homozygous individuals per 100 matings (aa)

A

B

C

Base

0

0.70 (0.000)

 

12.45 (0.000)

 

15.22 (0.000)

 
 

Strategyb

1

2

1

2

1

2

Low

10

0.70 (0.003)

0 (0.000)

9.11 (0.003)

8.17 (0.003)

12.42 (0.003)

6.77 (0.003)

 

20

0.70 (0.003)

0 (0.000)

7.43 (0.003)

7.48 (0.002)

6.06 (0.003)

5.97 (0.003)

 

30

0.70 (0.003)

0 (0.000)

6.08 (0.003)

6.47 (0.003)

6.05 (0.003)

5.92 (0.003)

Intermediate

40

0.70 (0.003)

0 (0.000)

5.21 (0.003)

5.69 (0.003)

4.80 (0.003)

4.87 (0.002)

 

50

0.70 (0.003)

0 (0.000)

5.05 (0.003)

5.12 (0.002)

4.75 (0.003)

3.87 (0.003)

 

60

0.70 (0.003)

0 (0.000)

4.58 (0.003)

4.59 (0.002)

4.7 5(0.003)

3.87 (0.003)

High

70

0.35 (0.003)

0 (0.000)

4.06 (0.003)

4.09 (0.002)

4.75 (0.003)

3.84 (0.003)

 

80

0.35 (0.003)

0 (0.000)

4.01 (0.002)

3.53 (0.002)

4.35 (0.003)

3.23 (0.003)

 

90

0.35 (0.002)

0 (0.000)

3.68 (0.003)

3.23 (0.002)

4.35 (0.002)

1.89 (0.001)

 

100

0.35 (0.003)

0 (0.000)

3.61 (0.003)

2.89 (0.002)

4.25 (0.003)

1.83 (0.002)

  1. aScenario A (7 loci with high-frequency LOF alleles), scenario B (76 loci with low-frequency LOF alleles), and scenario C (50 with high- and low-frequency loci)
  2. bSelection against carrier parents (strategy 1) and selection and mate allocation to avoid homozygous offspring (strategy 2)