Fig. 5

QTL analysis of chromosome 2 with variants color-coded according to predicted functional impact using SNPEff. a 1-Mb window of imputed whole genome sequence association data centred around top variant Chr2 g.111576221A>C (rs109979909) with the corresponding annotated gene track above. b 1-Mb window of imputed whole-genome sequence association data with rs109979909 fitted as a fixed effect. The red line indicates the genome-wide significance threshold p = 5 × 10⁻⁸