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Table 2 Significance of association between SNPs on chromosome 1 and tibial breaking strength in hens at 70 weeks of age

From: An eQTL in the cystathionine beta synthase gene is linked to osteoporosis in laying hens

Marker nameGalGal6 chr 1 position (bp)F statisticP valueHeterozygote effect (Newton)Homozygote effect (Newton)
Ost9236534890,332,8420.220.802  
Ost9988301597,883,8721.60.203  
Ost10141355699,395,4702.040.131  
Ost106225194104,084,0427.45< 0.0016.0816.02
Ost106460620104,314,8462.880.057  
Ost106823022104,678,8163.850.02212.772.62
Ost106940170104,834,9874.90.0086.33617.15
Ost107389494105,280,1276.30.00213.2− 1.65
Ost107766125105,655,6605.580.00412.614.83
Ost108015093105,901,0135.590.00412.694.82
Ost109151638107,036,7673.170.042− 7.75− 16.75
Ost109151769107,036,8983.170.0429.0016.75
Ost110373245108,261,2093.180.042− 0.58− 8.29
Ost110455031108,342,3965.490.0046.5918.46
Ost112374543110,246,4923.510.03− 2.98− 12.63
Ost112522587110,393,7176.340.0029.9216.55
Ost113740421111,546,5311.590.205  
Ost113743229111,549,3381.290.276  
Ost114648871112,392,6320.990.372  
Ost115611476113,329,3443.660.026− 3.8− 11.13
Ost115617544113,335,4120.440.647  
Ost115655839113,373,1562.470.085  
Ost115861595113,578,8761.970.14  
Ost115862305113,579,5861.780.17  
Ost115865281113,582,5621.40.248  
Ost115866264113,583,5450.160.92  
Ost121757410119,732,4540.20.821  
Ost121237272119,214,9846.190.013− 7.67 
Ost126455926124,863,2930.270.601  
Ost129219873126,721,1305.680.004− 46.2− 61.66
Ost134239048131,424,8650.140.872  
Ost134239237131,425,0540.140.872  
  1. F values were obtained by REML analysis with body weight, hatch, total eggs and eggs in the 3 days before death as fixed effects, and sire and dam as random effects. Effect sizes are quoted relative to the reference homozygote only for the SNPs that had a nominal significance level lower than 0.05. If corrected for multiple testing and taking the identification of seven blocks containing 23 SNPs using Haploview [40] into account, then the significance after Bonferroni correction should be set at 0.003. The SNPs passing this threshold are in italic characters. The additive effect represents half that of the homozygote reference