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Table 2 Significance of association between SNPs on chromosome 1 and tibial breaking strength in hens at 70 weeks of age

From: An eQTL in the cystathionine beta synthase gene is linked to osteoporosis in laying hens

Marker name GalGal6 chr 1 position (bp) F statistic P value Heterozygote effect (Newton) Homozygote effect (Newton)
Ost92365348 90,332,842 0.22 0.802   
Ost99883015 97,883,872 1.6 0.203   
Ost101413556 99,395,470 2.04 0.131   
Ost106225194 104,084,042 7.45 < 0.001 6.08 16.02
Ost106460620 104,314,846 2.88 0.057   
Ost106823022 104,678,816 3.85 0.022 12.77 2.62
Ost106940170 104,834,987 4.9 0.008 6.336 17.15
Ost107389494 105,280,127 6.3 0.002 13.2 − 1.65
Ost107766125 105,655,660 5.58 0.004 12.61 4.83
Ost108015093 105,901,013 5.59 0.004 12.69 4.82
Ost109151638 107,036,767 3.17 0.042 − 7.75 − 16.75
Ost109151769 107,036,898 3.17 0.042 9.00 16.75
Ost110373245 108,261,209 3.18 0.042 − 0.58 − 8.29
Ost110455031 108,342,396 5.49 0.004 6.59 18.46
Ost112374543 110,246,492 3.51 0.03 − 2.98 − 12.63
Ost112522587 110,393,717 6.34 0.002 9.92 16.55
Ost113740421 111,546,531 1.59 0.205   
Ost113743229 111,549,338 1.29 0.276   
Ost114648871 112,392,632 0.99 0.372   
Ost115611476 113,329,344 3.66 0.026 − 3.8 − 11.13
Ost115617544 113,335,412 0.44 0.647   
Ost115655839 113,373,156 2.47 0.085   
Ost115861595 113,578,876 1.97 0.14   
Ost115862305 113,579,586 1.78 0.17   
Ost115865281 113,582,562 1.4 0.248   
Ost115866264 113,583,545 0.16 0.92   
Ost121757410 119,732,454 0.2 0.821   
Ost121237272 119,214,984 6.19 0.013 − 7.67  
Ost126455926 124,863,293 0.27 0.601   
Ost129219873 126,721,130 5.68 0.004 − 46.2 − 61.66
Ost134239048 131,424,865 0.14 0.872   
Ost134239237 131,425,054 0.14 0.872   
  1. F values were obtained by REML analysis with body weight, hatch, total eggs and eggs in the 3 days before death as fixed effects, and sire and dam as random effects. Effect sizes are quoted relative to the reference homozygote only for the SNPs that had a nominal significance level lower than 0.05. If corrected for multiple testing and taking the identification of seven blocks containing 23 SNPs using Haploview [40] into account, then the significance after Bonferroni correction should be set at 0.003. The SNPs passing this threshold are in italic characters. The additive effect represents half that of the homozygote reference