Table 1 Summary of the structure of the simulated and real pedigrees and levels of investment
From: Evaluation of sequencing strategies for whole-genome imputation with hybrid peeling
Pedigree type | Pedigree depth (generations) | Generation size (individuals) | Population size (total individuals) | Level of investment (monetary units) | |||
|---|---|---|---|---|---|---|---|
0.5% at 2× | 1% at 2× | 2% at 2× | 5% at 2× | ||||
Simulated | 2 | 500 | 1000 | – | – | – | 10,000 |
2 | 1000 | 2000 | – | – | – | 20,000 | |
2 | 2000 | 4000 | – | – | 16,000 | 40,000 | |
5 | 500 | 2500 | – | – | 10,000 | 25,000 | |
5 | 1000 | 5000 | – | 10,000 | 20,000 | 50,000 | |
5 | 2000 | 10,000 | 10,000 | 20,000 | 40,000 | 100,000 | |
10 | 500 | 5000 | – | 10,000 | 20,000 | 50,000 | |
10 | 1000 | 10,000 | 10,000 | 20,000 | 40,000 | 100,000 | |
10 | 2000 | 20,000 | 20,000 | 40,000 | 80,000 | 200,000 | |
15 | 500 | 7500 | – | 15,000 | 30,000 | 75,000 | |
15 | 1000 | 15,000 | 15,000 | 30,000 | 60,000 | 150,000 | |
15 | 2000 | 30,000 | 30,000 | 60,000 | 120,000 | 300,000 | |
Real | ~ 20 | ~ 750 | ~ 15,000 | 15,000 | 30,000 | 60,000 | 150,000 |
~ 20 | ~ 1500 | ~ 30,000 | 30,000 | 60,000 | 120,000 | 300,000 | |
~ 20 | ~ 3250 | ~ 65,000 | 65,000 | 130,000 | 260,000 | 650,000 | |