Table 3 Breed-specific over-represented human-derived phenotypes as defined in the human GWAS catalogue
Breed | Human phenotype | Adjusted p-value | Overlapping genes |
|---|---|---|---|
Black Slavonian | Red vs brown/black hair colour | 3.37 × 10−20 | MC1R, TCF25, CHMP1A, FANCA, SPIRE2, CDK10, DPEP1, DEF8, CBFA2T3 |
Black Slavonian | Low tan response | 1.06 × 10−11 | DBNDD1, MC1R, CHMP1A, FANCA, SPIRE2, DEF8 |
Black Slavonian | Brown vs black hair colour | 2.81 × 10−06 | MC1R, TCF25, CDK10, DEF8 |
Black Slavonian | Blond vs brown/black hair colour | 1.49 × 10−04 | DBNDD1, MC1R, TCF25, CDK10, SPATA2L |
Cinta Senese | Blood protein levels | 2.63 × 10−02 | EDAR, GZMM, PRSS57, PRTN3, AZU1, ELANE |
Gascon | Red vs brown/black hair colour | 1.83 × 10−09 | TCF25, FANCA, SPIRE2, CBFA2T3 |
Krškopolje | Height | 8.46 × 10−05 | LYN, MOS, MC4R, SDR16C5, PLAG1, PENK, CHCHD7, RPS20 |
Krškopolje | Heel bone mineral density | 4.35 × 10−02 | MC4R, PLAG1, ACYP2, SPTBN1 |
Italian Landrace | Height | 6.91 × 10−05 | LYN, MOS, PLAG1, CHCHD7, NCAPG, RPS20, LCORL |
Italian Large White | Height | 3.50 × 10−04 | LYN, MOS, SDR16C5, GNPTAB, PLAG1, PENK, CHCHD7, RPS20 |
Moravka | Blood protein levels | 1.89 × 10−02 | PRTN3, NRTN, AZU1, CD36, ELANE |
Sarda | Height | 2.43 × 10−03 | LYN, MOS, PLAG1, CHCHD7, RPS20, SERPINI1 |