Genomic diversity and population structure of the Leonberger dog breed

Table 3 Private variants in mitochondrial DNA of Leonberger dogs

Gene	Variant designation^a	Proportion of variant^b	OMIM/OMIA number	Type
tRNA-Phe	m.49A > G	96%	590070	Unknown
tRNA-Val	m.1069 T > C	99%	590105	Unknown
ND2	m.4764 T > C; p.Ile284Thr	100%	516001	Missense
COX1	m.5681A > G	66%, 89%	516030	Synonymous
ND4	m.11211C > T	72%, 66%	516003	Synonymous
ND5	m.13118 T > C	62%	516005	Synonymous
ND5	m.13544A > G	100%, 100%, 100%, 100%	516005	Synonymous

^aAll positions refer to the CanFam3.1 reference sequence assembly
^bPercentage of variant represents heteroplasmy, 100% represents homoplasmy, for each dog that carries the variant calculated from the coverage of the affected mtDNA region

ISSN: 1297-9686