Fig. 2

Phenotype of affected calves. a Stillborn calf no. 23 (top) and 24 (bottom) after 272 and 269 days of gestation, respectively, with the characteristic tetradysmelia phenotype. b Pelvis of bovine calf no. 16 after 270 days of gestation. No acetabulae are developed, and instead of hindlimbs only irregular nodular clumps of mixed cartilaginous and osseous tissues are present in the disorganized musculature (black arrows). c Radiography of left hind leg of bovine calf no. 23 after 272 days of gestation. Bones of reduced size and deformed shape are developed