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Table 2 Summary of the results of the genome wide association analysis for sperm quality traits

From: A systems biology framework integrating GWAS and RNA-seq to shed light on the molecular basis of sperm quality in swine

SSC

Interval

#SNP

Interval Mbp

Top SNP

Top SNP location bp

Top SNP P-value

Top SNP FDR

Top SNP MAF

Beta

Trait

1

I1

1

–

rs339761632

13,501,755

4.64 × 10–8

0.02

0.06

4.84

PDROP

1

I2

8

82.90–83.49

rs81354986

82,895,619

1.69 × 10–6

0.03

0.07

5.05

HABN

1

I3

8

94.88–98.74

rs327733412

94,880,167

1.61 × 10–7

0.02

0.07

5.65

HABN

1

I4

1

–

rs337166779

126,397,198

2.05 × 10–6

0.03

0.06

5.02

HABN

1

I5

11

243.86–246.44

rs343194423

246,224,386

1.72 × 10–7

0.01

0.07

3.17

NABN

1

I6

2

258.54–258.55

rs332256425

258,548,786

1.76 × 10–6

0.04

0.06

3.44

NABN

3

I1

1

–

rs332055717

2,911,413

6.35 × 10–8

0.01

0.09

5.07

HABN

3

I2

3

113.75–113.84

rs328292697

113,750,595

1.09 × 10–7

0.01

0.07

3.41

NABN

4

I1

2

2.41–2.42

rs318575212

2,412,006

2.88 × 10–8

0.01

0.08

4.11

ACRO_5

rs332927981

2,415,239

6

I1

2

65.60–66.66

rs335394654

65,597,553

1.86 × 10–7

0.03

0.14

3.04

ACRO_5

7

I1

2

6.20–6.38

rs326239534

6,377,172

9.87 × 10–6

0.02

0.17

-9.15

MT_5

7

I2

2

85.73–86.88

rs336588919

86,884,279

4.13 × 10–8

0.01

0.06

3.75

NABN

9

I1

2

5.76–5.78

rs1110111787

5,776,597

1.55 × 10–7

0.02

0.07

5.43

HABN

9

I2

1

–

rs342738178

28,463,580

1.53 × 10–5

0.03

0.14

− 10.42

MT_5, MT_90

9

I3

1

–

rs328217450

137,959,590

4.77 × 10–8

0.02

0.18

2.36

R_ACRO

13

I1

18

25.36–28.47

rs690794887

25,535,100

3.06 × 10–7

0.02

0.14

3.78

HABN

13

I2

3

33.82–37.65

rs327865244

33,819,549

3.79 × 10–8

0.01

0.15

4.28

HABN

16

I1

1

–

rs324239602

6,476,358

6.08 × 10–6

0.01

0.46

9.07

MT_90

  1. SSC, Sus scrofa chromosome; #SNP, number of SNPs significantly associated (FDR) with the trait; Interval, region of the GWAS interval; Beta, additive effect; FDR, false discovery rate; MAF, minor allele frequency; ACRO_5, abnormal acrosomes 5 min; HABN, head abnormalities; NABN, neck abnormalities; PDROP, proximal droplets; R_ACRO, ratio acrosomes; MT_5, motility 5 min; MT_90, motility 90 min