Influence of genetics and the pre-vaccination blood transcriptome on the variability of antibody levels after vaccination against Mycoplasma hyopneumoniae in pigs

Table 3 Differentially expressed genes in blood before vaccination between groups of animals with divergent Ab responses to M. hyo vaccination at different days post-vaccination (dpv)

Type of Ab response	dpv	Classification	Number of differentially expressed genes	Differentially expressed genes with HUGO gene nomenclature committee symbol
Type of Ab response	dpv	Classification	Number of differentially expressed genes	Higher expression in "high" or "pos"	Higher expression in "low" or "neg"
Early (before booster)	21	High vs low	0
Early (before booster)	21	Negative vs positive	4 (4^a)		BARD1^a, LMBR1^a, TMEM236^a, CCDC158^a
Maximum (post booster)	28	High vs low	1 (1^a)		DNAH9^a
Maximum (post booster)	35	High vs low	0
Persistence (before slaughtering)	118	High vs low	52 (7^a)	TERB2^a, SMPD2, ELOVL1, NCLN, ZNF48, CLCN7, GSDMD, ULK2, ZNF668, TNFRSF18, PTPN18, PIM3, MARVELD1, PHB, ETNK2, HIST1H4H, ZNF787	TMTC3^a, ICE2^a, N4BP2, CCNC, LRIF1, AHI1, RPAP3, STK39, ABRAXAS1, FAM214A, TRAM1, ZNF280D, AEBP2, ZNF350, TAOK1
Persistence (before slaughtering)	118	Negative vs positive	0

ISSN: 1297-9686