Fig. 6

Associations of polymorphic STRs (pSTRs) with annual mean temperature and altitude among Chinese indigenous pigs. Manhattan plots of P values corresponding to the association of pSTRs with annual mean temperature (a) and altitude (b) of geographical regions where the indigenous breed originated. The genes intersecting with ± 5-kb flanking regions of the top STRs that show the highest \({\text{R}}_{{{\text{st}}}}\) values are indicated by red arrows. c, d Representative examples of distributions of STR dosages corresponding to the annual mean temperatures in the METTL8 (c) and FAM155B genes (d). e, f Representative examples of distributions of STR dosages corresponding to the altitude values in the EPAS1 (e) and PDK1 genes (f). In c–f, the structure of the genes is plotted according to the GTF files from Ensembl (release 95) using customized R scripts. The black arrows in the genes indicate the transcripts that are encoded by the positive or negative strand of the genome. The red arrows indicate the location of STRs in the corresponding genes