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Table 2 Number of significant associations between the 12 genotyped miRNA SNPs and the whole set of mRNAs expressed in the gluteus medius (GM) skeletal muscle (N = 89) and liver (N = 87) tissue samples from Duroc pigs

From: Variability in porcine microRNA genes and its association with mRNA expression and lipid phenotypes

SNP (chromosome position)

Type

Significant associations

GM (P-value < 0.05)

LIVER (P-value < 0.05)

GM (q-value < 0.1)

LIVER (q-value < 0.1)

rs81349391 (1:164,026,014 bp)

ssc-miR-339 apical loop (A/G)

456

356

0

0

rs344472188 (2:13,296,736 bp)

ssc-miR-130a apical loop (A/G)

320

1252

0

1

rs333787816 (2:65,308,181 bp)

ssc-miR-23a precursor stem (T/C)

2075

751

6

1

rs340704946 (4:6,948,743 bp)

ssc-miR-30d precursor stem (A/G)

563

398

0

0

rs320008166 (6:56,427,227 bp)

ssc-miR-371 precursor stem (T/C)

270

365

2

8

rs323906663 (6:63,491,948 bp)

ssc-miR-429 precursor stem (G/A)

328

406

2

8

rs319154814 (9:9,581,989 bp)

ssc-miR-326 apical loop (G/A)

372

2400

0

0

rs321151601 (9:39,280,312 bp)

ssc-miR-34c mature region (C/A)

947

392

0

0

rs341950320 (12:36,947,510 bp)

ssc-miR-378-2 precursor stem (G/A)

792

322

0

0

rs334680106 (13:100,083,229 bp)

ssc-miR-15b precursor stem (C/T)

277

205

0

0

rs335924546 (17:10,758,828 bp)

ssc-miR-486 precursor stem (C/T)

1232

171

0

0

rs334590580 (18:18,341,582 bp)

ssc-miR-335 precursor stem (T/C)

665

219

1

0

  1. This is a condition-free association analysis in which all expressed mRNAs are taken into account regardless of the existence of miRNA–mRNA complementarity and the availability of functional data validating miRNA–mRNA interactions in humans (see “Methods” for more information)