Table 2 Peak variants for composite milk production traits with highly significant protein sequence association effects

FP

5

75698283

rs385866519

1

4.0e−19

rs207628090

0.979

CSF2RB

M

c.41 T > C

FP

11

103304757

rs109625649

0

4.3e−46

rs109625649

1

PAEP

M

c.401 T > C

FP

12

69608900

rs211406918

0

4.2e−33

rs208744187

0.951

TGDS

M

c.204A > C

FP

14

1732043

rs437406031

1

7.2e−37

rs450710918

0.990

ENS..39978

M

c.352G > A

FP

14

1732043

rs437406031

1

7.2e−37

rs476736066

0.997

MROH1

M

c.3549G > C

FP

14

1800439

rs209876151

0

8.9e−2225

rs109326954

0.9999

DGAT1

M

c.695C > A

FP

14

1800439

rs209876151

0

8.9e−2225

rs134364612

0.9998

SLC52A2

M

c.724A > G

LP

3

15433518

rs109749506

1

1.3e−20

rs382689947

0.995

TENT5A

M

c.1237 T > C

LP

3

15433518

rs109749506

1

1.3e−20

rs134844772

0.992

GBA

M

c.1080C > A

LP

3

15433518

rs109749506

1

1.3e−20

rs109330809

0.992

MTX1

L

c.508-6 T > C

LP

3

15545091

rs379353107

0

2.2e−42

rs109816684

0.998

SLC50A1

L

c.282 + 7G > A

LP

6

38027010

rs43702337

0

9.0e−717

rs43702337

1

ABCG2

M

c.1742A > C

LP

16

24983926

rs110162358

2

1.0e−19

rs109896036

0.999

MTARC1

L

c.628-5C > T

LP

16

24983926

rs110162358

2

1.0e−19

rs110899826

0.999

MTARC1

M

c.581C > G

LP

19

43036265

rs210324533

3

9.4e−40

rs207799702

0.944

KAT2A

L

c.700-7C > G

LP

19

43036265

rs210324533

3

9.4e−40

rs209410283

0.945

KCNH4

M

c.408C > G

LP

19

43036265

rs210324533

3

9.4e−40

rs377779402

0.945

KCNH4

H

c.2663 + 2 T > C

PP

3

15550598

rs380597285

0

1.7e−37

rs109816684

0.994

SLC50A1

L

c.282 + 7G > A

PP

5

75758989

rs210094995

0

3.3e−34

rs209394772

0.935

CSF2RB

M

c.227G > A

PP

5

75758989

rs210094995

0

3.3e−34

rs210937722

0.926

NCF4

M

c.841G > C

PP

5

118239754

rs384479185

2

3.9e−32

rs456403270

0.976

TBC1D22A

M

c.1063C > T

PP

6

38027010

rs43702337

0

6.4e−115

rs43702337

1

ABCG2

M

c.1742A > C

PP

14

1763380

rs135017891

0

5.9e−718

rs135258919

0.999

HSF1

M

c.1031 T > C

PP

14

1802265

rs109234250

1

1.2e−61

rs109234250

1

DGAT1

M

c.694G > A

PP

14

1802265

rs109234250

1

1.2e−61

rs134364612

0.999

SLC52A2

M

c.724A > G

PP

15

53940444

rs382926661

1

2.9e−20

rs380220394

0.992

DNAJB13

L

c.69-4 T > C

PP

19

43035006

rs209494359

0

1.6e−40

rs207799702

0.944

KAT2A

L

c.700-7C > G

PP

19

43035006

rs209494359

0

1.6e−40

rs209410283

0.945

KCNH4

M

c.408C > G

PP

19

43035006

rs209494359

0

1.6e−40

rs377779402

0.945

KCNH4

H

c.2663 + 2 T > C