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Fig. 2 | Genetics Selection Evolution

Fig. 2

From: Integration of a single-step genome-wide association study with a multi-tissue transcriptome analysis provides novel insights into the genetic basis of wool and weight traits in sheep

Fig. 2

Detection of tissues and cell types related to wool traits and live weight in sheep. a Functional enrichment analysis of tissue-specific genes (the top 10% of genes based on t-statistics) for 13 organ systems (central nervous system (CNS), cardiovascular system (Cardio), skin, muscle, liver, lung, kidney, gastrointestinal (GI) tract, endocrine (Endoc), immune system, male reproductive system (Male_R), female reproductive system (Fem_R), and embryonic system). b–d Relationships between the six economic traits and the 13 organ systems, GI tract tissues and immune tissues, respectively. The colour corresponds to the enrichment degree (i.e., − log10FDR), which was computed by sum-based GWAS signal enrichment analysis based on the top 10% tissue-specific genes and a 20-kb extension. *corrected-P (FDR) < 0.05

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Genetics Selection Evolution

ISSN: 1297-9686