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Table 2 Number of significant variants (N) (P < 10–5 and P < 10–6) and their false discovery rates (FDR, %) for each trait from the single-trait GWAS and multi-trait GWAS

From: A conditional multi-trait sequence GWAS discovers pleiotropic candidate genes and variants for sheep wool, skin wrinkle and breech cover traits

Traita

P < 10–5

P < 10–6

N

FDR

N

FDRb

ygfw

1891

15.1

716

4.0

agfw

2164

13.2

910

3.1

ycfw

1145

24.8

606

4.7

acfw

1153

24.8

274

10.4

ysl

2182

13.1

1166

2.4

asl

753

37.9

103

27.7

yfd

1340

21.2

314

9.1

afd

312

91.4

16

 

ydcv

3162

9.0

1722

1.7

adcv

1301

21.9

493

5.8

ycuv

682

41.8

145

19.7

acuv

562

50.8

183

15.6

yss

2516

11.3

1547

1.8

ass

1611

17.7

911

3.1

ebwr

1174

24.3

518

5.5

ebcov

354

81.0

14

 

M-GWAS

9879

2.9

7431

0.4

  1. N number of significant variants, M-GWAS multi-trait GWAS
  2. aTrait names are as defined in Table 1
  3. bFDR in empty cells are either not available or higher than 100%
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Genetics Selection Evolution

ISSN: 1297-9686