Runs of homozygosity in Swiss goats reveal genetic changes associated with domestication and modern selection

Table 3 Description of the 15 ROH islands shared among the 217 individuals from the modern breeds

Chr	Start pos	End pos	Average fraction modern breeds	Average fraction Bezoar	Genes annotated in ROH regions
3	110,837,228	110,952,170	84.94	21.28	CD84, LOC102170372, SLAMF1
5	36,289	216,534	88.58	53.86	No genes
5	98,924,460	99,173,351	94.59	33.57	LOC108636060, LOC102183506
8	70,737,252	74,882,654	86.15	42.62	STC1, LOC102183600, APTX, DNAJA1, SMU1, B4GALT1, SPINK4, BAG1, CHMP5, NFX1, AQP7, AQP3, NOL6, UBE2R2, UBAP2, DCAF12
9	91,295,758	91,426,085	86.01	83.13	DLL1, FAM120B
10	17,036,648	17,211,934	84.75	27.09	PROX2, YLPM1, FCF1
13	53,007,666	53,319,681	95.31	73.16	MYT1, OPRL1, LKAAEAR1, RGS19, TCEA2, PRPF6, SAMD10, DNAJC5, TPD52L2, ZBTB46
13	56,416,469	56,517,376	80.75	29.76	ZNF831
14	22,802,897	22,937,158	82.65	33.03	ZFPM2
15	32,098,192	32,367,622	84.46	50.56	RHOG, STIM1, RRM1, LOC108637588, LOC102177547
17	8,865,949	8,935,273	81.32	88.89	LOC108637850, LOC102177554
18	15,526,880	15,552,439	82.90	88.89	CBFA2T3
20	71,475,167	71,668,860	95.43	45.68	SLC9A3, EXOC3, AHRR
29	45,996,028	46,047,264	82.44	74.07	PTDSS2, ANO9, IFITM5
29	50,476,146	50,541,044	81.81	88.89	LOC102176024
Total			87.00	44.64

Chr: chromosome number; Start pos: start position of each ROH island; End pos: end position of each ROH island;
Average fraction for the individuals of the modern breeds sample (N = 217) and average fraction for the individuals from wild bezoar (N = 9)
Rows entirely in italic characters indicate ROH islands that are only seen in modern breeds, and not in Bezoar goats (homozygous bezoar goats < 55%)

ISSN: 1297-9686