Functionally prioritised whole-genome sequence variants improve the accuracy of genomic prediction for heat tolerance

Table 1 Number of informative markers for heat tolerance defined as ‘top SNPs’ selected from single-trait GWAS and multi-trait meta-analyses of heat tolerance slope traits of Holstein discovery cow set (N = 20,623)

Markers were selected based on the GWAS cut-off thresholds of − log10(p-value) ≥ 2 and − log10(p-value) ≥ 3. The values in brackets are the final number of SNPs after adding selected ‘top SNPs’ to the 50k SNP data used in the BayesRC analyses (i.e., 42,572 SNPs + top SNPs). Traits are defined as heat tolerance milk (HTMYslope), fat (HTFYslope) and protein (HTPYslope) yield slope traits

ISSN: 1297-9686