A genome-wide screen for resilient responses in growing pigs

Table 1 Genomic regions associated with body weight deviation from expected growth (∆BW) after the vaccine challenge

SSC	Region^a (Mb)	SNP^b	p-value	BF	%GV^c	Candidate genes^d
2	10.7–12.7	rs81240151	8.92E−07	695.9	6.4	CD5^e,g, CD6^e,f,g, LPXN^e,g, PRPF19^f,g, TMEM109^f,g, SLC15A3^e,h, DTX4^g, PTGDR2^g, STX3^g, MS4A2^g, MS4A8^g, MS4A10^g, MS4A13^g, MS4A15^g
8	12.8–14.8	rs322129753	3.35E−05	202.3	4.45	LCORL^h, SLIT2^e,g
9	135.8–138.7	rs81310044	3.22E−05	27.3	13.75	IKZF1^e, FIGNL1^f,g, GRB10^g,h
		rs81323569	6.36E−06	134.6
		rs81419253	3.26E−05	34.6
		rs81419361	2.27E−06	395.9
		rs81282478	1.61E−05	53.2
		rs81334739	1.61E−05	52.7
11	59.3–61.7	rs323869641	6.39E−05	34.4	2.35	GPC5^e
11	59.3–61.7	rs80828177	5.66E−05	84.3

SSC Sus scrofa chromosome, BF Bayes factor
^aAssociated genomic region
^bSNP identified as associated
^cProportion of the genetic variance of ∆BW explained by the associated genomic region
^dCandidate genes involved in immune response^e, response to stress^f, signal transduction^g, or growth^h

ISSN: 1297-9686