Table 1 Differentially-expressed pathways in domesticated versus wild embryos
KEGG functional group | KEGG sub-group | KEGG pathway | p value | Direction of perturbation | Sac fry [20] | Feeding fry [20] |
|---|---|---|---|---|---|---|
Cellular processes | Cell communication | Focal adhesion | 0.00051 | Two-way perturbed | Â | Â |
Gap junction | 0.00036 | Two-way perturbed | Â | Â | ||
Environmental information processing | Signal transduction | Hippo signaling pathway | 0.00040 | Two-way perturbed | Up-regulated | Â |
MAPK signaling pathway | 0.00101 | Two-way perturbed | Â | Â | ||
NF-kappa B signaling pathway | 0.00021 | Two-way perturbed | Down-regulated | Down-regulated | ||
Wnt signaling pathway | 0.00213 | Two-way perturbed | Up-regulated | Â | ||
Signaling molecules and interaction | Cell adhesion molecules (CAM) | 0.00069/0.00144 | Up-regulated/two-way perturbed | Â | Â | |
Cytokine-cytokine receptor interaction | <0.00001 | Two-way perturbed | Down-regulated | Â | ||
Neuroactive ligand-receptor interaction | 0.00001 | Two-way perturbed | Two way perturbed | Down-regulated | ||
ECM-receptor interaction | 0.00016 | Down-regulated | Â | Up-regulated | ||
Organismal systems | Circulatory system | Vascular smooth muscle contraction | 0.00032 | Two-way perturbed | Â | Â |
Development | Osteoclast differentiation | 0.00019 | Two-way perturbed | Two way perturbed | Â | |
Digestive system | Mineral absorption | 0.00011 | Up-regulated | Â | Â | |
Pancreatic secretion | 0.00164 | Two-way perturbed | Â | Up-regulated | ||
Salivary secretion | 0.00117 | Two-way perturbed | Â | Â | ||
Endocrine system | GnRH signaling pathway | 0.00014 | Two-way perturbed | Â | Â | |
Immune system | Chemokine signaling pathway | 0.00017 | Two-way perturbed | Down-regulated | Down-regulated | |
Fc epsilon RI signaling | 0.00026 | Two-way perturbed | Down-regulated | Down-regulated | ||
Natural killer cell mediated cytotoxicity | 0.00004 | Two-way perturbed | Â | Â | ||
T cell receptor signaling pathway | 0.00002 | Two-way perturbed | Â | Â | ||
Nervous system | Glutamatergic synapse | 0.00154 | Two-way perturbed | Down-regulated | Â | |
Long-term potentiation | 0.00001 | Two-way perturbed | Â | Â | ||
Genetic information processing | Translation | Ribosome | 0.00383 | Up-regulated | Up-regulated | Â |
RNA transport | 0.00174 | Up-regulated | Up-regulated | Â | ||
Metabolism | Carbohydrate metabolism | Fructose and mannose metabolism | 0.00183 | Up-regulated | Â | Â |
Galactose metabolism | 0.00168 | Up-regulated | Â | Â | ||
Energy metabolism | Carbon fixation in photosynthetic organisms | 0.00494 | Up-regulated | Â | Up-regulated | |
Glycan biosynthesis and metabolism | Glycosphingolipid biosynthesis—lacto and neolacto series | 0.00316 | Up-regulated |  |  | |
Lipid metabolism | Sphingolipid metabolism | 0.00229 | Up-regulated | Â | Â |